Premier Biotech Help Center
A resource outlining answers to common questions regarding our drug testing products, laboratory services, customer solutions and additional helpful information. Have a question that is not answered here? Require additional assistance? We would appreciate the opportunity to help. Please contact us directly via email and one of our experienced support staff will contact you back shortly.
Frequently Asked Questions
Why does the BUP strip take longer and more faint compared to other drug strips?
The Premier Bio-Cup is testing for BUP at 5ng/mL. Because we are testing at such a sensitive level, which studies indicate is necessary to effectively detect BUP use, the test chemistry takes a bit longer than other test lines to form and tends to form a lighter line because of the low cut-off level. It is very important to remember that it is completely normal for the BUP line to take longer to form and be less intense (lighter) than the surrounding test strips. Make sure to wait the full 5 minutes before calling a BUP line positive.
What does a lab confirmation test tell us?
The LC-MS/MS laboratory confirmation provides a specific and definitive result. Lab confirmation testing will indicate the exact compound in the sample ie. It WILL differentiate whether the OPI positive result was due to heroin, codeine, hydrocodone, morphine, or a combination of these. The confirmation result is absolutely specific and definitive. Premier Biotech will provide toxicology testimony if necessary so that results are upheld in court.
What are the differences between screening and confirmations?
Screening refers to a preliminary test that yields a qualitative “Positive or Negative” result. Screening can be conducted with a rapid test or using laboratory instrumentation (EIA, EMIT). Both rapid tests and lab screens use the same testing technology, called immunoassay technology. Screening technology is non-specific in that it does not differentiate among the drug class. For example, a positive OPIATE result only indicates that there is some opiate present. It does not indicate whether it is hydrocodone (vicodin), codeine (tylenol 3), heroin, or a combination of these.
Confirmation testing utilizes high complexity instrumentation that yields a definite and specific result. Best practice for confirmation testing involves using either a GC/MS or LC-MS/MS. The results of a confirmation test provide an absolute and definite result that indicates the specific drug/compound present in the urine or oral fluid sample. Premier Biotech utilizes all LC-MS/MS instrumentation for confirmation testing which is considered to be the platinum standard. LC-MS/MS results are defensible in court.
Would someone taking Vicodin report a presumptive positive for both the OPI and OXY strip?
If a donor is taking Tylenol-3. Would they report a presumptive positive result for oxycodone?
Why do some test (T) lines appear more faint than others?
Does the Opiate Strip pick up Oxycodone?
What cross reacts with the standard opiate (OPI) panel?
Why would EDDP be advantageous over a test for MTD?
In many cases, the test administrator would like to know if the individual is actually taking their prescribed methadone and not diverting it. If you are using a standard methadone test you cannot tell the difference as you can sprinkle some MTD from a tablet into the sample and you will get a positive. If you use an EDDP test, you are testing for the MTD metabolite which allows you to make sure the person is taking their recommended dose.
Additionally, you will also pick up the abuser that is not prescribed and is just abusing it.
EtG negative, EtS positive...Alcohol consumption?
EtG can degrade. EtS is present, alcohol was consumed.
Why would THC be negative in the rapid cup while positive on a lab confirmation?
Cutoff for THC is much lower via the confirmation method. Low result may not be enough to be detected within a cup.
Why are cutoffs lower with confirmation testing compared to rapid test devices?
Screening technology is less specific than mass spec (LC/MS/MS, GC/MS) technology. It is recommended to have presumptive positive results confirmed at the lab.
Would adderall be picked up on the methamphetamine strip?
No. Adderall would only test positive for amphetamine.